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As it is known, certified reference materials (CRM) are used frequently and often compulsory in laboratory analysis. A reference standard substance is a substance whose one or more measurable values can be defined by internationally valid methods or methods and determined as a standard value. If a detailed information document about this defined standard value is created and this document contains, for example, which analyzes were used to obtain this standard value, the methods by which the results were validated, which chemicals were used in the analyzes, then this document is called a certificate. When such a certificate is created for the reference substance, the name of the product becomes the certified reference standard substance.